Gel de PRP versus ácido hialurónico versus corticosteroides para la artrosis de rodilla: ensayo clínico prospectivo aleatorizado
DOI:
https://doi.org/10.63403/re.v33i2.480Palabras clave:
Osteoartrosis de rodilla, Plasma rico en plaquetas, Infiltración intraarticular, gel de PRP, ácido hialurónicoResumen
Introducción: las infiltraciones intraarticulares son ampliamente utilizadas en el tratamiento de la osteoartrosis de rodilla, aunque persiste controversia sobre la estrategia más eficaz y duradera.
Objetivos: comparar los resultados clínicos del gel de plasma rico en plaquetas (PRP), el ácido hialurónico y el corticosteroide intraarticular, utilizados de forma aislada o combinada, en pacientes con osteoartrosis de rodilla.
Resultados: todos los grupos presentaron mejoría clínica temprana. A los 6 meses, los tratamientos que incluyeron gel de PRP mostraron beneficios más sostenidos en dolor y función en comparación con el corticosteroide aislado. La combinación de gel de PRP, ácido hialurónico y corticosteroide presentó los resultados más consistentes.
Conclusión: la combinación de gel de PRP, ácido hialurónico y corticosteroide mostró una mejoría clínica consistente y sostenida a los 6 meses en comparación con el corticoide aislado, aunque no se observaron diferencias estadísticamente significativas entre los grupos tras el ajuste. El gel de PRP utilizado de forma aislada mostró resultados clínicos comparables al ácido hialurónico.
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Derechos de autor 2026 Diego Ariel de Lima, Renata Clazzer, Carlos Eduardo da Silveira Franciozi, Lana Lacerda Lima, Maria Luzete Costa Cavalcante, Camilo Partezani Helito, Sergio Marinho de Gusmão Canuto
Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0.
Esta obra se publica bajo una Licencia Creative Commons Atribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0). Los autores conservan los derechos de autor.
